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Search Results for " liver disease "

20

Compounds

Cat No. Product Name Synonyms Targets
T12580 PTUPB COX , Epoxide Hydrolase
PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).
T2601 Vidofludimus SC12267,4sc-101 Dehydrogenase , DNA/RNA Synthesis , Interleukin
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
T5S1923 Schisandrin C Schizandrin-C,Wuweizisu-C Apoptosis , Others , Virus Protease
Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.
T0456 Cinchophen Cinconal COX
Cinchophen (Cinconal), an analgesic drug, is utilized in treating gout.
T2171 SEW​2871 SEW2871 S1P Receptor , LPL Receptor
SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...
T3053 CZC-25146 CHEMBL2397014 LRRK2
CZC-25146 (CHEMBL2397014) is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM for wild-type LRRK2(Leucine-rich repeat kinase-2) and G2019S LRRK2, respectively.
T5139 CZC-25146 hydrochloride LRRK2
CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.
T1090 Perphenazine Perphenazin,Etaperazine,Trilafon CaMK , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
T9010 IMM-H007 Others , AMPK
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
T7060 Amantadine 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine Others
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.
T1406 Amantadine hydrochloride 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride Dopamine Receptor , Influenza Virus
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
T38715 MSDC-0602K MSDC-0602K,Azemiglitazone potassium PPAR
MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (...
T37184 CX08005 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid Phosphatase
CX08005 is a protein tyrosine phosphatase 1B inhibitor. CX08005 reduces hepatic lipid accumulation and microcirculatory impairment associated with non-alcoholic fatty liver disease.
T0080 Trapidil Rocornal,Trapymine,Avantrin,Trapymin,AR-12008 PDGFR , PDE
Trapidil (Avantrin) is a coronary vasodilator agent. It was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
T21977 P-Cresyl sulfate Others
p-Cresyl Sulfate is a major uremic toxin found in the blood of patients with chronic kidney disease (CKD), derived from the metabolites of tyrosine and phenylalanine in the liver.
TQ0223 Lusutrombopag S-888711,Mulpleta Thrombin , Thrombopoietin Receptor
Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
T0461L Berberine sulfate AI3-61947,Berberin sulfate,Berberine sulphate,Berberal
Berberine sulfate (Berberal) is a quaternary ammonium salt of the benzylisoquinoline alkaloid proto-berberines, which can be used in the study of type 2 diabetes mellitus, abdominal obesity and metabolism-related fatty l...
T6752 S-Adenosyl-L-methionine disulfate tosylate Ademetionine disulfate tosylate DNA/RNA Synthesis
S-Adenosyl-L-methionine disulfate tosylate (Ademetionine disulfate tosylate) is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activi...
T3804 Neomangiferin Mangiferin 7-glucoside Phosphatase
Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar...
T50000 2-Iodohippuric Acid Others
2-Iodohippuric Acid can be used to measure renal clearance for renal function studies, and for the diagnosis of certain diseases, such as liver and kidney disease. In addition, it is used in the synthesis of certain drug...

Compounds

PTUPB
T12580
Synonym:
Target: COX, Epoxide Hydrolase
Vidofludimus
T2601
Synonym: SC12267,4sc-101
Target: Dehydrogenase, DNA/RNA Synthesis, Interleukin
Schisandrin C
T5S1923
Synonym: Schizandrin-C,Wuweizisu-C
Target: Apoptosis, Others, Virus Protease
Cinchophen
T0456
Synonym: Cinconal
Target: COX
SEW​2871
T2171
Synonym: SEW2871
Target: S1P Receptor, LPL Receptor
CZC-25146
T3053
Synonym: CHEMBL2397014
Target: LRRK2
CZC-25146 hydrochloride
T5139
Synonym:
Target: LRRK2
Perphenazine
T1090
Synonym: Perphenazin,Etaperazine,Trilafon
Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
IMM-H007
T9010
Synonym:
Target: Others, AMPK
Amantadine
T7060
Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine
Target: Others
Amantadine hydrochloride
T1406
Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride
Target: Dopamine Receptor, Influenza Virus
MSDC-0602K
T38715
Synonym: MSDC-0602K,Azemiglitazone potassium
Target: PPAR
CX08005
T37184
Synonym: 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid
Target: Phosphatase
Trapidil
T0080
Synonym: Rocornal,Trapymine,Avantrin,Trapymin,AR-12008
Target: PDGFR, PDE
p-Cresyl sulfate
T21977
Synonym:
Target: Others
Lusutrombopag
TQ0223
Synonym: S-888711,Mulpleta
Target: Thrombin, Thrombopoietin Receptor
Berberine sulfate
T0461L
Synonym: AI3-61947,Berberin sulfate,Berberine sulphate,Berberal
Target:
S-Adenosyl-L-methionine disulfate tosylate
T6752
Synonym: Ademetionine disulfate tosylate
Target: DNA/RNA Synthesis
Neomangiferin
T3804
Synonym: Mangiferin 7-glucoside
Target: Phosphatase
2-Iodohippuric Acid
T50000
Synonym:
Target: Others
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TargetMol